Hi Reno, VERY TRUE !!
I encounter the same problem when converting from Raw. Must shoot below ISO 400 if not there is noise for d200! That will only happen when, Sharpess is MAX out at 100, Luminance is 0. Color Noise dont really affect, but i leave it at 10.
Cause i want sharpness, so i totally remove out the Luminance. Set it to 0. Because the 80-400 is not that sharp as prime, have to sacrifice noise in the pic for sharpness.
For example when i use the 50 1.4, it is so sharp, i can afford to put some luminance control to about 50 percent and still, the image is very sharp.
For the 80 400, to counter that noise, i make luminance to 0, sharpenss to Max at 100, then, after that use filter and make noise reduction to 100 percent. Note that when it is at noise reduction at 100 percent, all the noise is gone totally at Iso 800 and below, but the pic becomes totally soft !So, i layer out the area that i want it to be sharp.
overall good pic with photoshop.
Cheers