I'm a male with small hands. To me 600D fits OK, and it's relatively lightweight. It's just that I prefer more external control buttons offered by 60D, so I chose 60D.
Anyway like what others have suggested, you might want to visit Canon showroom yourself to try to play with both models. Each model offers different weights, ergonomics, and degree of controls. These might be important factors you can only feel yourself, not from the technical specs.