Hi. Lemme share my experiences.
I'm not a Canon user. I use the Epson 1290 A3+ printer. Sucks up ink like nobody's business and it doesn't have individual colour ink-tanks. One colour out, must change the whole stupid cartridge (and they call it the "intelligent cartridge" - HA!).
So when I saw CIS (I*kstati*n) systems, thought they'd be a super way to save money. And the demo prints and promo brochures look quite good. So why not? But the reality is, they are more trouble than they're worth. The cartridge is not precision-made, could not fit properly so it cracked all the contact pins on my printhead!!! No need to imagine how troublesome it was to lug an A3+ printer by public transport from Woodlands to Commonwealth to get it fixed. And the cost!
Then when I finally did get it running, I was faced with constant head-clogging and air-bubbles in the system. I must have ran the clean-head process a billion times. And at best, it turned out a merely-acceptable print-out. Leave for 2 days, head clogs and air bubbles again. Apply shampoo, lather, rinse, repeat.
In the end (with my wife nagging "I told you so"), I ditched the system. For everyday normal, low-value prints, I'd use the better third party cartridges (PioneerTech not bad). But for critical work, it's nothing but originals for me. Damn expensive, but not much choice really.
Then again, some people seem to be very happy with their CIS systems. Even the same brand I used. Guess it's really a hit-or-miss affair. But if I may add in a final word, it would be: DON'T
(Hope this helps, somewhat.)