Road RUnner seems more catered to photography gear than other stuff like clothes.
If you want a bigger capacity for carrying non-photography stuff, the Orion Aw may be a good alternative. You can't carry as much equipment though and there's no wheels.
http://www.lowepro.com/pages/series/trekking/orionaw.htm
Lowepro's highly popular, convertible beltpack/backpack for active, outdoor SLR photographers -- a regular on Everest, the winner of an Industrial Design Excellence Award and a legend around the world.
If you want a bigger capacity for carrying non-photography stuff, the Orion Aw may be a good alternative. You can't carry as much equipment though and there's no wheels.
http://www.lowepro.com/pages/series/trekking/orionaw.htm
Lowepro's highly popular, convertible beltpack/backpack for active, outdoor SLR photographers -- a regular on Everest, the winner of an Industrial Design Excellence Award and a legend around the world.