I own a beat-up leica 35mm/f2 (Type1) and previously owned a 35mm/f1.4 which I sold within a week. I do use the leica lens on a Canon 10D regularly for instant gratification. Focusing is not so easy on the 10D, but stopped down aperture priority exposures are fairly accurate. I shoot wide open and therefore I get automatic aperture priority exposure using this lens on the 10D.
The Leica had noticeable vignetting but the colour, sharpness, contrast and bokeh are excellent WIDE open. You should get a lens shade (which is a rare and expensive item) to control flare .
The problem with the canon lens is not so much a sharpness or colour issue, but a problem controlling highlights. WIDE open, the purple fringing was too much to bear and it affected the image quality. The effect is akin to the image from a high end point-n-shoot with small plastic lens. The purple fringing does go away when you stop down substantially. You can test this at any shop before buying. Shoot the shiny metallic surfaces. Of course, away from strong highlights, the lens performs well enough.
The Canon 35mm L and 135mm L are considered to be legendary lenses. In the end, I kept only the 135mm.
Ultimatel, when I'm dealing with more fluid scenes, I'd primarily be shooting wide open, otherwise to MF wide open and then stop down to the needed aperture would mean I could lose the shot. However when dealing with static subjects then I could take all the time I wanted as long as the light didn't change. I've read that the Leica is very good at controlling flare and there is hardly any even under challenging conditions. However in that sense maybe there are differences between the type 1 and type 2 versions.
CA is one of the pet peeves I've had with a number of lenses, but I don't mind them as much as distortion, which I find much more objectionable...barrel distortion especially.