I have not really tried the EF 70-300mm f/4.5-5.6 DO IS USM, can't really comment on it. Sometime, I did own a EF 70-200 f/4L USM, but I don't like the color, a little warm, optical is ok, but not my kind... However, if you want a faster lens then go for 70-200 f/4L, otherwise for range, go...